• What Is imsi?
  • imsi Procedure
  • Why Choose Kasturi imsi ?
  • Do's And Dont's

A high-magnification digital imaging microscope is used in IVF treatment to evaluate and select sperm for microinjection into the egg. This procedure is known as intracytoplasmic morphologically chosen sperm injection (IMSI).

Our experts are better able to evaluate the sperm's structure using the IMSI technique, and they can prevent the sperm with suspected mutations from being injected into the available eggs.

Another treatment carried out during IVF is known as intracytoplasmic sperm injection (IMSI), or IMSI. It enables medical professionals to distinguish between the sperm's structural changes and rule out any real ones. When injecting into the egg, doctors carry out this process while using a high magnification digital imaging microscope.

In IMSI, a variation of ICSI, sperm samples is studied under a nearly 6000-fold more powerful microscope to better understand their "morphology." The embryologist can spot minute sperm head flaws at a kind of higher magnification than is possible with traditional ICSI.

It is advised in people who have a history of repeated implantation failures, recurrent ICSI failures, or severe teratozoospermia despite the fact that it has not yet been proven to be beneficial for all individuals needing sperm injection (abnormal sperm shape).

Essentially, it uses to serve as a selection tool to help embryologists select the best sperm for ICSI. IMSI might not be the best procedure for you if your sperm count or motility is already so low that it restricts the amount of sperm accessible for ICSI.

Why perform an IMSI?

An IMSI treatment enhances the likelihood that an embryo will be fertilized and will develop normally, especially in men who have had previous IVF treatments using intracytoplasmic sperm injection (ICSI) that did not go well as well as in men who have large amounts of defective sperm.

Specialists can pick out faulty sperms from the sperm sample using digital technology to magnify them by around 6000 times. The sample of sperms that will be used to fertilize the egg is subsequently reduced to remove these aberrant sperms.

To improve the likelihood of the procedure's success, this certified sample of sperms is subsequently employed in an ICSI IVF therapy.

Step 1: Semen sample preparation

•   The semen sample is first cleaned of any impurities using a particular solution after being collected.

•  On the day of the IMSI process, an embryologist uses centrifugation to isolate the viable cells.

Step 2: Sperm selection

   Under a microscope, an embryologist sorts through the sperms to select the best one to inject into the egg.

•   IMSI uses a high magnification of roughly 6600X to help identify sperm morphology. Only sperm with normal morphology is selected by the embryologist for injection into the egg.

•  These sperms increase the likelihood of conception. Even the smallest and most numerous vacuoles are visible to us. Sperms with abnormally large heads and huge vacuoles are not chosen. Choosing the most viable sperms is much easier in this method.

Step 3: Egg selection

Under ultrasound guidance, a needle is transvaginally inserted to aspirate the egg follicles and collect the eggs. The eggs are first cleaned with an enzyme to remove undesirable elements after egg harvest. After that, it is examined using an inverted microscope to select eggs that are healthy.

Step 4: Sperm injection

The chosen sperm is then put into a pipette and inserted into the egg while being observed under a microscope. The microinjected eggs are then cultured overnight in an incubator in a sterile culture Petri plate.

Furthermore, the microinjected eggs are monitored on a regular basis to look for evidence of fertilization. The embryos are placed inside the uterus after they have formed.

A urine pregnancy test is performed two weeks later to confirm pregnancy and determine the next course of action.


Shree IVF clinic is renowned for being a location where you don't lose hope, where we help you complete your family, and where couples come but return as parents. With all these amazing ideas, our specialists created their creation.

For advanced assisted reproduction and advanced pelvic surgery, there is Kasturi Clinic.

Following an IUI process, the list of Dos and Don'ts is clearly explained below.

  • Returning to regular activities the same day following an IUI procedure is actually not an issue. If one is at ease with it, one can begin working out or even doing errands practically immediately.
  • After an IUI procedure, there is no requirement for bed rest, travel limitations, or even diet maintenance. After an IUI procedure, one can rest for a few days if they feel like it or if they are uncomfortable. Following the Dos and Don'ts after IUI is mandatory.
  • After receiving IUI therapy in Hyderabad, there are no restrictions on having intercourse. In truth, it will support the procedure and produce fruitful outcomes.
  • If there is pain or even cramping after the given process, one needs to avoid NSAIDs or pain medicines. • If there is bleeding while the process is on, one needs to avoid sex for roughly 48 hours.
  • It is advisable to wait two weeks before taking a pregnancy test in order to reduce the risk of false positives. Do's and Don'ts after IUI are necessary because the implantation of the delivered embryo actually takes a few days after ovulation. Additionally, it takes a few days for one's hormone levels to rise; only then will they change, and one will then be able to see the desired outcomes.
  • In fact, the doctor may administer hormone assistance to aid in the implantation of the selected embryo. These can come in the form of suppositories that are placed in the vagina or oral medications that are administered orally.
  • Although there is no indication that swimming interferes with the IUI technique, swimming should be avoided for about 48 hours.

Dietary and Lifestyle Modifications Linked to IUI

If you are going to choose to undergo the IUI or IVF procedure, you must make specific dietary and lifestyle adjustments. You should check out the Dos and Don'ts following IUI.

Eat as many fruits, nuts, and leafy vegetables as you can; avoid processed foods; avoid eating seafood that contains too much mercury; eat six small meals each day; include quinoa, brown rice, and other complex carbs in your diet; and stay away from hot, spicy foods that aggravate indigestion. Nothing, not even asafoetida, should be added to the food. Fruits such as grapes, papaya, and pineapple should be avoided since they might induce bleeding and the breakdown of the endometrial layer. This might result in a miscarriage.

Although there are conflicting views on this, it is the best to consult your doctor.

Don’ts after IUI Procedure

  • You should avoid sitting on the floor, suddenly leaning forward or backward, or doing anything that puts pressure on your lower abdomen, especially after IVF.
  • If you need to bend over to pick something up off the floor, it is best to bend your knees, get down, and take it instead of bending over to the waist.
  • Reduce your intake of tea, coffee, or caffeine to about 2-3 cups per day or less.
  • Refrain from wearing anything weighing more than 5 kg. Holding the item close to your body will help you maintain good balance and reduce the chance of falling.
  • Refrain from going up and down the stairs too quickly.
  • Aim to space out your trips to no more than 2-3 hours.
  • Get enough rest—it requires at least 8 hours of sleep—and pay close attention to the days immediately following the embryo transfer. Always get enough sleep at night. Prenatal care is crucial at this point.

Dr. M. Kalpana (DNB, OBGYN, Obstetrician & Gynaecologist Fertility Specialist Fetal Medicine Specialist)

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