Recurrent pregnancy loss is defined as the occurrence of 3 or more consecutive pregnancy loss and clinically-recognized pregnancy involuntarily ending before 20 weeks. A clinically-recognized pregnancy means that the pregnancy is been seen on an ultrasound or that pregnancy tissue will been identified after a pregnancy loss.
CAUSES RECURRENT PREGNANCY LOSS:
Most of the pregnancy losses will be result from chromosomal, or genetic, abnormalities, & are random events. The abnormality can come from the egg, the sperm, or from the early embryo. Around 12-15% of all clinically recognized pregnancies end in the miscarriage. Even though, it was estimated that at least 30-60% of all conceptions are end within the first 12 weeks of the gestation. Up to 50% of the time, the woman won’t even realize that she was ever pregnant. The risk of the miscarriage is increasing with the number of previous pregnancy losses, but in general it is less than 50%.
Advancing maternal age is been linked with an increased risk of the miscarriage, which is thought to be because of poor egg quality that leading to the chromosomal (genetic) abnormalities. Sometimes, the mother or father themselves may be having a slight abnormality in their genes, but the offspring can be more severely affected & thus result in the miscarriage.
Sometimes, there could be abnormality in the uterus (the womb) also and which leads to the miscarriage. The miscarriage may be because of poor blood supply to the pregnancy or inflammation. Some women will be born with an irregularly shape of uterus, & some women may also develop abnormalities with their uterus over time.
A woman’s immune system will also play a major part in recurrent pregnancy loss. Hormone abnormalities can also impact in the pregnancy loss, which includes thyroid disease & diabetes. Abnormalities in a mother’s blood clotting can also affect the pregnancy loss.
Usually speaking, environmental factors, stress, & occupational factors won’t seems to be related to the pregnancy loss.
RECURRENT PREGNANCY LOSS TREATMENT:
The treatment which was recommends for the patients with the recurrent pregnancy loss are depends on the underlying cause of the recurrent pregnancy loss. No matter what is the results of the work-up are, the chance of a successful future pregnancy is high: 77% if the work-up showed no abnormalities, & 71% if an abnormality was found.